The principles underlying the use of powder diffraction data in solving pharmaceutical crystal structures.
نویسندگان
چکیده
Solving pharmaceutical crystal structures from powder diffraction data is discussed in terms of the methodologies that have been applied and the complexity of the structures that have been solved. The principles underlying these methodologies are summarized and representative examples of polymorph, solvate, salt and cocrystal structure solutions are provided, together with examples of some particularly challenging structure determinations.
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عنوان ژورنال:
- Acta crystallographica. Section C, Crystal structure communications
دوره 69 Pt 11 شماره
صفحات -
تاریخ انتشار 2013